English Explanatory Dictionary

Philadelphia chromosome

English dictionary entry

Meanings

noun
  1. Human chromosome 22, after it has, pathologically, traded some of its genetic material with chromosome 9; this often causes chronic myelogenous leukemia.

Word forms

Philadelphia chromosome Philadelphia chromosomes

Etymology

The abnormality was first discovered and described in 1959 by David Hungerford from the Institute for Cancer Research and Peter Nowell from the University of Pennsylvania School of Medicine. Both facilities are located in Philadelphia, Pennsylvania.

Synonyms

Ph chromosome
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